Two New Studies Find Aggressive Prostate Cancer May Be Linked to Ancestral Heritage

資源中心分類:Global Express
Source https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-022-01096-w

Two studies published simultaneously by Jaratlerdsiri et al in Nature and Gong et al in Genome Medicine have identified genetic signatures explaining ethnic differences in the severity of prostate cancer, particularly in sub-Saharan Africa. Through genetic sequencing of prostate cancer tumors from Australian, Brazilian, and South African donors, the research team identified a new prostate cancer taxonomy, as well as cancer drivers that may not only distinguish patients by genetic ancestry, but also predict which cancers are likely to become life-threatening—a task that currently proves challenging.